- Curcumin seems to target specific molecules or pathways that control the cell cycle. It also blocks inflammatory cytokines and enzymes, including cyclooxygenase-2 (COX-2), That’s why studies have shown that it can be helpful for people with osteoarthritis (OA). For example, a 2021 review of 15 randomized controlled trials found curcumin relieved OA pain and stiffness as well or better than nonsteroidal anti-inflammatories (NSAIDs) like ibuprofen and celecoxib – minus potentially serious side effects.
- Other research suggests that low doses of curcumin may help restore a normal balance between T cells that cause inflammation (Th17 cells) and those that protect against it (regulatory T cells). An imbalance in these cells is believed to drive rheumatoid arthritis and other autoimmune diseases.
Ref: Linda Rath | Updated March 1, 2023. https://www.arthritis.org/health-wellness/healthy-living/nutrition/antiinflammatory/ turmeric-wont-help-arthritis